NARCAN
DuPont Pharma
Naloxone HCl sub: buprenorphine/naloxone
Narcotic Antagonist ( 6 mg) (2 mg) = 8 mg,thats what i take
the naloxone is what made me not a candidate for sedation for the endosocopy)
Action And Clinical Pharmacology: Naloxone prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension.
Naloxone is an essentially pure narcotic antagonist which does not possess the 'agonistic' or morphine-like properties characteristic of other narcotic antagonists. It does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotic or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.
In the presence of narcotic addiction, naloxone will produce withdrawal symptoms; it has not been shown to cause addiction.
Mechanism of Action: While the mechanism of action is not fully understood, the preponderance of evidence suggests that naloxone antagonizes the opioid effects by competing for the same receptor sites.
When naloxone is administered i.v. the onset of action is generally apparent within 2 minutes; the onset of action is only slightly less rapid when it is administered s.c. or i.m. The duration of action is dependent on the dose and route of administration of naloxone. I.M. administration produces a more prolonged effect than i.v. administration. The requirement for repeat doses of naloxone, however, will also be dependent upon the amount, type and route of administration of the narcotic being antagonized (see Warnings).
Following parenteral administration, naloxone is rapidly distributed in the body. It is metabolized in the liver, primarily by glucuronide conjugation, and excreted in urine. In one study the serum half-life in adults ranged from 30 to 81 (mean 6412) minutes. In a neonatal study the mean plasma half-life was observed to be 3.10.5 hours.
Single s.c. doses of naloxone as high as 24 mg/70 kg (0.343 mg/kg) and multiple doses of 90 mg daily for 2 weeks administered to normal volunteers produced no behavioral or physiologic changes, yet its antagonistic activity to subsequent morphine challenge persisted.
Indications And Clinical Uses: The complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the agonist-antagonist analgesics such as pentazocine, butorphanol and nalbuphine.
Also indicated for the diagnosis of suspected acute opioid overdosage.
Just wanted to send you a HUGE HUG(((((((((((((((((((((((()))))))))))))))))))))))))))))))Ive missed you Jewels!!!
Love Molly
Love Molly
Jewels not sure where you were going with this, but the narcan in the suboxone means nothing. It is only put there to stop a user from shooting it up, nothing more. It isn't absorbed sublingually.
The narcan had nothing to do them not knocking you out. It was the bup, that is and always will be that only active ingredient. It is what blocks the opiates and makes things get sticky at times when medical attention is needed......
The narcan had nothing to do them not knocking you out. It was the bup, that is and always will be that only active ingredient. It is what blocks the opiates and makes things get sticky at times when medical attention is needed......
i posted this about narcan, i didnt know that was the other name for naloxone.when i take an 8 mg tablet i am getting 6 mg bup and 2 mg naloxone (narcan) i came home and googled narcan when the nurse approached me at my procedure and told me that i could not have any sedation because the NARCAN will throw the sedation off. so i posted this for others to learn thanks julie
jewels,
Sorry to say, but the nurse was not correct ..... The Bupe (active ingredient in Suboxone and Subutex) is the actual opiate blocker.
There are ways to get around it .... seems to me that the Dr's and nurses you were involved with did not have the right info about Sub to have spared you the torture you went thru ..... I'm so sorry and feel very bad for you!!!
In the future, if you (or anyone else on Sub) needs to have sedation for a medical procedure / surgery / etc and have a bit of notice first, discuss with a very knowledgable Sub Dr / addiction specialist about stopping the Sub before the procedure .... It makes a huge difference.
Also, your Suboxone is actually 8 mgs of bupe and 2 mgs of naloxone,
not 6 and 2.
Hope this helps you some.
Also ... somehow ALL of my saved e-mail addys have been deleted so I no longer have yours. Can you send it to me again?? My addy is cherriswizzle@yahoo.com
Happy Thursday!!!!!
But you are wrong and you are not listening, and you should be as you take this drug and don't understand it which isn't to cool....
YOU DO NOT ABSORD THE NAXOLONE SUBLIGUALLY....
It really is that simple. There are two forms of this.
Subutex ( just buprenorphine ), no naxolone and yes it can be abused, shot up......
There is also suboxone ( buprenorphine again ) with that naxolone. Why so you can't shoot it up. That simple and that is the only reason it is there so the buprenorphine can't be abused.
Not to repeat myself but the buprenorphine is the active ingredient and will always be. It is what made what happened to you happen. No matter what the nurse said, she is wrong, didn't research right and missing what the naxolone is there for, as a fail safe for those who were using by needle. That love of the needle is as hard to break as the love of the drug in it.....
Buprenorphine is an extremely powerful opaite. In itself, and the way it attaches to the receptors is the blocker. It is what would render a person to not feel the effects of other opaites. It is also what presents and causes all the problems when they need to sedate.
Make no mistake it is there always, it is an opiate....And if anyone where to use on top other opiates, mix in doses of benzo's death could be found. Just because no high is felt with buprenorphine that doesn't mean it doesn't do anything. It can help push an untimely death......
And oddly narcan may not work with a sub od which is written in the sub literature...Go figure, more confusion to an already complicated drug.
YOU DO NOT ABSORD THE NAXOLONE SUBLIGUALLY....
It really is that simple. There are two forms of this.
Subutex ( just buprenorphine ), no naxolone and yes it can be abused, shot up......
There is also suboxone ( buprenorphine again ) with that naxolone. Why so you can't shoot it up. That simple and that is the only reason it is there so the buprenorphine can't be abused.
Not to repeat myself but the buprenorphine is the active ingredient and will always be. It is what made what happened to you happen. No matter what the nurse said, she is wrong, didn't research right and missing what the naxolone is there for, as a fail safe for those who were using by needle. That love of the needle is as hard to break as the love of the drug in it.....
Buprenorphine is an extremely powerful opaite. In itself, and the way it attaches to the receptors is the blocker. It is what would render a person to not feel the effects of other opaites. It is also what presents and causes all the problems when they need to sedate.
Make no mistake it is there always, it is an opiate....And if anyone where to use on top other opiates, mix in doses of benzo's death could be found. Just because no high is felt with buprenorphine that doesn't mean it doesn't do anything. It can help push an untimely death......
And oddly narcan may not work with a sub od which is written in the sub literature...Go figure, more confusion to an already complicated drug.
Yup, your nurse is wrong. My friend had two surgeries on his foot and both times he was sedated and given anestesia (sp.?) for the procedure. He has taken sub for about 6 months. Jimmy told the dr.s of his opiate addiction and they were cool with it. He has some 800 mg Ibuprofens for the pain, but the medication they gave him for sedation worked just fine.
(((((((((((((((((((((((((((jewels))))))))))))))))))))))))))))))))))))))))
hello dear, goos morning........
winnies here all cuddled up with me in the blankets......
how are your babies??
jewels i totally unerdstand why the nurse thought that...........
we push narcan post op when feel a "code" comming on.......
we run our own codes.......
and it reverses everything.........
and after we give that.....whooo..its like a the pain meds are gone..if we push narcotics its not effective.......for a while
so we make sure we really HAVE to push the narcan cause it works SO good to reverse the narcotics...........
its ok jewels........this disease gets complicated and i am trying to learn about sub myself........
i want to make sure i am educated about it cause i am a cricital care nurse and i have recovered tons of patients and what i find if a patient is an addict or a recovering addict they will NOT TELL US..........
and I DONT BLAME THEM>>>>>>NOT ONE BIT.........
cause opions change so fast and like brooke said in another thread.....
i agree and thats just me..........
i always ask...quietly....by there ear..."will you please tell me if you take pain pills at home"
cause i am pushing meds and its not working......
so i just want to know so if i have to give them twice as more to controlll their pain.........I WILL. in my department they just got off the the OR table and just got their body cut open and its up to me to make sure the pain is tolerable.
all patients are entitiled to good pain mamagement ..no matter what...
they cant take what i am giving them home and most likely they wont even remember that part of their recovery........
when they reach our criteria then we send them to the second part of recovery...
and they will remember the second part because they are out of the crirical stage............
just wanted to say HI jewels and that i love you.........
i will never forget that you prayed for winnie when i was in flordia and some folks here thought i was stupid for worring about winnie..........
but in the end she is all i have..........
so i will never forget that for as long as i live........
have a nice day.............
hello to everyone that posted here.....**HUGS**
God Bless you all............
thumper
hello dear, goos morning........
winnies here all cuddled up with me in the blankets......
how are your babies??
jewels i totally unerdstand why the nurse thought that...........
we push narcan post op when feel a "code" comming on.......
we run our own codes.......
and it reverses everything.........
and after we give that.....whooo..its like a the pain meds are gone..if we push narcotics its not effective.......for a while
so we make sure we really HAVE to push the narcan cause it works SO good to reverse the narcotics...........
its ok jewels........this disease gets complicated and i am trying to learn about sub myself........
i want to make sure i am educated about it cause i am a cricital care nurse and i have recovered tons of patients and what i find if a patient is an addict or a recovering addict they will NOT TELL US..........
and I DONT BLAME THEM>>>>>>NOT ONE BIT.........
cause opions change so fast and like brooke said in another thread.....
i agree and thats just me..........
i always ask...quietly....by there ear..."will you please tell me if you take pain pills at home"
cause i am pushing meds and its not working......
so i just want to know so if i have to give them twice as more to controlll their pain.........I WILL. in my department they just got off the the OR table and just got their body cut open and its up to me to make sure the pain is tolerable.
all patients are entitiled to good pain mamagement ..no matter what...
they cant take what i am giving them home and most likely they wont even remember that part of their recovery........
when they reach our criteria then we send them to the second part of recovery...
and they will remember the second part because they are out of the crirical stage............
just wanted to say HI jewels and that i love you.........
i will never forget that you prayed for winnie when i was in flordia and some folks here thought i was stupid for worring about winnie..........
but in the end she is all i have..........
so i will never forget that for as long as i live........
have a nice day.............
hello to everyone that posted here.....**HUGS**
God Bless you all............
thumper
This really makes me angry, its lazy nursing.
The nurse saw "Naloxone (Narcan)" and acted without thinking. Too smart by half.
A nurse should know that Narcan is administered IV/IM, and that a sublingual dose is not absorbed.
The nurse saw "Naloxone (Narcan)" and acted without thinking. Too smart by half.
A nurse should know that Narcan is administered IV/IM, and that a sublingual dose is not absorbed.
ok ok, i wasnt refusing to listen, believe me i have researched sub, but no where did it say the naloxone wasnt absorbed into the body if you took it sublingually, that is none of articles i read.
ok i am still confused then, help me out here.
so if naloxone isnt absorbed into the body sublingually, then why can the buprenorphine?
next question, is it not possible to have say a general anesthesia while on sub?
ok when kee kee broke her ankle, she was on sub and they without her permission gave her demoral and then she used pain medication at home for a few days, isnt that an opiate on top of an opiate? and kee kee if you read this post did the sub stop you from feeling the high from the demoral and was it vicodin? did it relieve the pain despite the sub in your system?
man i am so pissed that i had to suffer something that may haunt me the rest of my life, it all happened so fast, the day of the procedure as a matter of fact when i called the doctor before hand to discuss the fact that he had planned to first use as the tech explained to me "a high dose of valium" for sedation, obviously he didnt research it too good either, isnt valium a benzo? that is what made me call him, then he had planned to use fentanyl! the other nurse asked the misinformed nurse couldnt she at least have versad? the nurse said nope!
my bad, i posted that wrong , i meant to say 8 mg bup and 2 mg naloxone, when i posted 6/2 i was thinking 6 +2=8, duh!
i love you too thumper, you are a doll !
ok i am still confused then, help me out here.
so if naloxone isnt absorbed into the body sublingually, then why can the buprenorphine?
next question, is it not possible to have say a general anesthesia while on sub?
ok when kee kee broke her ankle, she was on sub and they without her permission gave her demoral and then she used pain medication at home for a few days, isnt that an opiate on top of an opiate? and kee kee if you read this post did the sub stop you from feeling the high from the demoral and was it vicodin? did it relieve the pain despite the sub in your system?
man i am so pissed that i had to suffer something that may haunt me the rest of my life, it all happened so fast, the day of the procedure as a matter of fact when i called the doctor before hand to discuss the fact that he had planned to first use as the tech explained to me "a high dose of valium" for sedation, obviously he didnt research it too good either, isnt valium a benzo? that is what made me call him, then he had planned to use fentanyl! the other nurse asked the misinformed nurse couldnt she at least have versad? the nurse said nope!
my bad, i posted that wrong , i meant to say 8 mg bup and 2 mg naloxone, when i posted 6/2 i was thinking 6 +2=8, duh!
i love you too thumper, you are a doll !
(1) some drugs can be absorbed sub-lingually (bupe, anginine), others can't (like narcan). The narcan is there to stop you crushing up and IV'ing the bupe.
(2) yes you can have a general anaesthetic while on sub, there are a range of anaesthetic drugs that have no interaction with bupe, but the anaesthetist must know you are on bupe.
(3) you could have been sedated with a benzo, since the risk of over-sedation is low with medical personnel present.
(4) You can use opiates over the of bupe if you are strictly supervised by qualified personnel who know how to treat respiratory depression and other signs of OD.
(5) It is difficult to get high from opiates while on bupe, because the amount needed to beat the bupe blocker puts you at risk of overdose (see 4).
(2) yes you can have a general anaesthetic while on sub, there are a range of anaesthetic drugs that have no interaction with bupe, but the anaesthetist must know you are on bupe.
(3) you could have been sedated with a benzo, since the risk of over-sedation is low with medical personnel present.
(4) You can use opiates over the of bupe if you are strictly supervised by qualified personnel who know how to treat respiratory depression and other signs of OD.
(5) It is difficult to get high from opiates while on bupe, because the amount needed to beat the bupe blocker puts you at risk of overdose (see 4).
